The body heals itself when injured by sending platelets, which carry growth factors, to the injured area. These growth factors initiate new blood circulation and new cell formation to repair the injured area by sending chemical signals, like emails and faxes to the surrounding area, which multiplies the growth factors thereby increasing their healing properties.

When PRP is placed on an injured tendon, ligament, muscle, skin, or bone it regenerates the injured tissue. The faster the healing, the less cellular damage, the sooner the rehabilitation and the better the end result. This is the basis of Platelet Rich Plasma Therapy (PRP).

Whole blood is drawn and centrifuged to separate the blood components; RBC’s, WBC’s, proteins and platelets. Essentially, the percentage of platelets and RBC’s are reversed so that PRP contains over 90% platelets and about 4% RBC’s when compared to whole blood, hence the name platelet rich plasma.
Platelets are really only cell fragments, derived from the megakaryocyte, but when activated, will release cytokines or (growth factors) that regulate the entire wound healing cascade. In PRP, there are concentrated platelets with seven fundamental protein growth factors; platelet derived growth factor PDGF (AA, BB), epidermal growth factor (EGF), transforming growth factor (TGF beta 1, beta 2), vascular endothelial growth factor (VEGF), insulin derived growth factor (IGF), fibroblastic growth factor (FGF) and platelet derived angiogenesis factor (PDAF).
Additionally, PRP also contains three proteins known to act as cell adhesion molecules; (fibrin, fibronectin and vitronectin. These proteins are essential components for osteoconduction and as a matrix for bone, connective tissue and epithelial migration. (Note: It is our theory that, since hair is made of protein, concentrating these essential proteins along with the growth factors works synergistically to promote hair growth and hair canal formation).

Growth factors are present in the hair follicles “ bulge area”, where stem cells are found, and they interact with cells of the matrix, thus activating the proliferative phase of the hair. Stem cells are more primitive and they give origin to the epidermal cells and the sebaceous glands. Cells of the dermal papilla, which are found at the capillary base, are of mesenchymal origin. Both cells need each other, and when they interact through the action of various growth factors they will give rise to the future follicular unit.
Over the past three years and 200 plus bio-surgical hair transplantation procedures this author has witnessed hair growth sooner in grafted hairs, more mature growth sooner and an increased overall aesthetic density when compared to hair transplantation without PRP.
Please proceed to the Surgical Section of the web site to see our results and read more about Bio Cellular Surgical hair restoration.
If your are interested in Non-Surgical PRP treatments proceed to the Non- Surgical PRP section at the top of the HOME page.
Proceed to the Ortho Biologic PRP section on the top of the HOME page for information regarding non surgical injections for tendon, ligament and sports related injuries.